Financial life in a big town

January 21, 2012

Novartis drug investigated after 11 deaths

Filed under: Loans, stocks — Tags: , , , — Silver @ 7:24 am

A multiple sclerosis drug made by industry giant Novartis is under investigation after at least 11 patients taking the medicine died.

The drug, Gilenya, was licensed last year in the European Union to treat patients with a severe type of multiple sclerosis.

The deaths raise concerns Gilenya could trigger heart problems after patients take their first dose, according to a statement issued Friday by the European Medicines Agency. The agency, which is now investigating the drug, said it isn’t clear if it caused the deaths.

One of the deaths was in the U.S., where a patient died within 24 hours of taking the first dose.

The European agency said it didn’t know where the other 10 deaths occurred, but that they were reported to its drug database, which monitors side effects from medicines in the European Union.

A spokeswoman at the U.S. Food and Drug Administration said it also is conducting a data analysis but has not made any definitive conclusions and does not know when its review will be complete.

More than 30,000 patients have taken Gilenya worldwide payday loan. The European Medicines Agency advised doctors to increase their monitoring of patients after the first dose of the medicine. The agency said the risk of a slow heart rate after the first dose of Gilenya was known when it was approved.

Novartis AG said it was advising doctors of new recommendations on using Gilenya. They had previously recommended all patients be monitored for six hours after their first dose, but are now tightening that to include continuous heart monitoring using electrocardiograms and measuring blood pressure and heart rate every hour. In certain patients, that monitoring should be extended, the drug maker said in a statement.

This new guidance applies only to patients taking their first dose, Novartis said in a statement.

The EU drug regulator hopes to finish its review of the drug by March.

Source

December 30, 2011

Stocks rebound: Dow up 136 points, S&P back in black

Filed under: legal, stocks — Tags: , , , — Silver @ 6:48 pm

U.S. stocks rose Thursday in a thinly-traded session as investors focused on signs of strength in the economy before calling it a year.

The Dow Jones industrial average () rose 136 points, or 1.1%, to end at 12,287. The S&P 500 () added 13 points, or 1.1%, to 1,263. The Nasdaq () gained 24 points, or 0.9%, to 2,614.

Thursday’s rebound put the S&P 500 back on track for a modest 0.4% gain in 2011, after the broad market index fell sharply Wednesday. The Dow is currently up 6.1% for the year, while the Nasdaq is set for a 1.5% loss.

Stocks were supported by reports on housing, manufacturing and employment that raised hopes about the U.S. economy.

"Today’s last round of major U.S. reports before the weekend New Year’s celebration provided a decidedly positive spin to the outlook," wrote Michael Englund, chief economist at Action Economics, in a note to clients.

Traders said low volume, typical of the holiday week, has led to more pronounced swings, and some of the moves are coming from year-end portfolio rebalancing rather than convictions over the trajectory of the market or particular stocks.

Are you a markets whiz?

"We expect light trading through today and tomorrow, and any noise can create wild swings," said Doug Cote, chief market strategist at ING Investment Management.

Looking ahead, many investors expect stocks to move higher in the first few months of 2012.

The U.S. economy has shown signs of improvement recently, with economists forecasting a 3.3% increase in gross domestic product in the final three months of 2011. In addition, corporate profits are expected to rise in the fourth quarter, continuing an 11-month streak.

But the outlook for next year remains clouded by the debt crisis in Europe, which continues to weigh on demand for risk assets such as stocks.

On Thursday, an auction of Italian 10-year bonds, which have seen yields continue to flirt with the 7% danger zone, provided muted results. While yields were reported below prior levels, demand was short.

The euro fell to a 17-month low and analysts warn the currency could fall even further in 2012.

"Europe is a powder keg and could explode at any time, and likely will when we are the most complacent," said Keith Springer, president of Springer Financial Advisors in Sacramento cash advance america.

Economy: Jobless claims rose 15,000 to 381,000 in the latest week, according to the U.S. Labor Department. Analysts surveyed by Briefing.com had expected 368,000 claims.

But the figure remained below 400,000, giving investors hope that the labor market will strengthen in the new year.

The National Association of Realtors index of pending home sales, which measures signed sales contracts but not closed sales, rose 4% to a seasonally adjusted annual rate of 4.42 million in November from 4.25 million in October.

Economist had expected the a 0.6% increase in pending home sales.

The report boosted shares of homebuilders, including Pulte (, Fortune 500), Masco (, Fortune 500), Lennar () and DR Horton (, Fortune 500).

An index of manufacturing activity in the Chicago area eased slightly in December but held near a 7-month high, according to the Institute for Supply Management.

Companies: Amazon (, Fortune 500) eased after analysts at Goldman Sachs (, Fortune 500) suggested that the online retailer’s sales growth for the holiday period may fall short of expectations.

Shares of Yahoo (, Fortune 500) gained 2.7% after reports that China’s Alibaba Group has hired a lobbying firm to prepare a bid for Yahoo.

BP () edged higher despite reports that employees could face criminal charges in relation to last year’s Gulf of Mexico oil spill.

World markets: European stocks closed higher. Britain’s FTSE 100 () added 0.8%, the DAX () in Germany rose 0.9% and France’s CAC 40 () rose 1.1%.

Asian markets ended mixed. The Shanghai Composite () edged up 0.2%, the Hang Seng () in Hong Kong fell 0.7% and Japan’s Nikkei () lost 0.3%.

Betting on the dollar in 2012

Currencies and commodities: The dollar gained strength against the euro and the British pound but fell versus the Japanese yen.

Oil for February delivery rose 31 cents to $99.05 a barrel.

Gold futures for February delivery fell $23.20 to $1,540.90 an ounce.

Bonds: The price on the benchmark 10-year U.S. Treasury rose, with the yield easing to 1.89% from late Wednesday.  

Source

December 26, 2011

King Says Crisis Threatens Europe

Filed under: online, stocks — Tags: , , , — Silver @ 2:42 am

+%3Cp%3EMervyn+King%2C+vice+chairman+of+the+European+Systemic+Risk+Board%2C+said+Europe%92s+sovereign+debt+crisis+is+threatening+to+hurt+the+real+economy+and+the+outlook+for+financial+stability+has+worsened.+%3C%2Fp%3E+%3Cp%3EGrowth+prospects+%93have+deteriorated%94+since+September%2C+King%2C+who+is+also+governor+of+the+Bank+of+England%2C+said+at+a+briefing+hosted+by+the+European+Central+Bank+in+Frankfurt+yesterday.+%93Investors+lack+confidence+to+continue+to+provide+normal+levels+of+funding.+Dependence+on+central+banks+has+risen.%94+%3C%2Fp%3E+%3Cp%3EThe+ECB+loaned+banks+a+record+489+billion+euros+%28%24636+billion%29+for+three+years+on+Dec.+21+to+avert+a+credit+crunch+from+the+sovereign+debt+crisis.+The+central+bank+said+earlier+this+week+that+the+turmoil+has+taken+on+systemic+proportions+not+seen+since+the+2008+collapse+of+Lehman+Brothers+Holdings+Inc.+%3C%2Fp%3E+%3Cp%3EKing+said+the+outlook+for+financial+stability+has+%93worsened%94+since+the+last+ESRB+meeting+in+September%2C+and+while+intervention+by+the+ECB+is+expected+to+%93assuage+funding+problems+in+the+near+term%2C+in+the+longer+term+private+funding+markets+must+be+revitalized.%94+%3C%2Fp%3E+%3Cp%3EBank+shares+have+suffered+this+year+as+borrowing+costs+surged+in+the+euro+region.+The+Stoxx+600+Banks+Index+has+fallen+28+percent+since+the+end+of+June%2C+compared+with+a+12+percent+decline+by+the+Stoxx+Europe+600.+%3C%2Fp%3E+Capital+Plea++%3Cp%3EKing+also+appealed+to+banks+not+to+%93reduce+lending+to+the+real+economy%94+as+they+increase+their+capital+levels+to+meet+new+standards+set+by+regulators.+%3C%2Fp%3E+%3Cp%3E%93We+are+very+conscious+there+is+extreme+risk+aversion+in+private+financial+markets%2C%94+he+said+%3Ca+href%3D%22http%3A%2F%2Fus-fast-cash-now.com%22%3Ecash+advance%3C%2Fa%3E%3C%21–+.+–%3E.+%93We+want+a+more+robust+banking+system+so+that+whatever+risks+crystallize%2C+whatever+their+source%2C+the+banking+system+is+in+a+better+position+than+2008.%94+%3C%2Fp%3E+%3Cp%3EThere+was+%93no+discussion%94+at+the+ESRB+meeting+of+any+country+leaving+the+euro+area%2C+King+said.+Still%2C+%93all+financial+institutions+are+advised+to+prepare+for+a+wide+range+of+contingencies%2C%94+he+said.+%3C%2Fp%3E+%3Cp%3EAndrea+Enria%2C+the+second+ESRB+vice+chair+who+is+also+the+chairman+of+the+European+Banking+Authority%2C+said+he+is+%93disappointed%94+by+European+leaders+dithering+over+putting+rescue+measures+in+place%2C+effectively+delaying+Europe%92s+bank+recapitalization.+%3C%2Fp%3E+%3Cp%3E%93We+have+always+been+quite+adamant+in+all+occasions%2C+also+in+the+debate+running+up+to+the+decision%2C+that+this+should+have+been+a+comprehensive+package%2C%94+Enria+said.+This+includes+%93recapitalization%2C+some+measures+–+funding+guarantees+–+addressing+the+funding+problems+and+strengthening+of+the+European+Financial+Stability+Facility+and+of+the+tools+to+deal+with+the+sovereign+crisis.%94+%3C%2Fp%3E+%3Cp%3EThe+ESRB%2C+which+aims+to+warn+of+brewing+risks+in+the+financial+system%2C+was+set+up+in+January+as+part+of+a+new+European+architecture+designed+to+ward+off+another+financial+crisis+such+as+that+which+followed+the+Lehman+collapse.+Its+65-+member+board+is+headed+by+ECB+President+Mario+Draghi.+%3C%2Fp%3E++%3Cp%3E%3Ca+href%3D%27http%3A%2F%2Fwww.bloomberg.com%2Fnews%2F2011-12-23%2Fking-says-crisis-threatens-europe-s-economy-as-stability-outlook-worsens.html%27+rel%3D%27nofollow%27%3ESource%3C%2Fa%3E%3C%2Fp%3E+

November 29, 2011

Americans in November more confident about economy

Filed under: economics, stocks — Tags: , , , — Silver @ 3:08 pm

Americans’ confidence in the economy in November bounced back to its highest level since July, the latest sign that they are beginning to feel more cheerful about spending during the holiday shopping season.

The Conference Board, a private research firm, says Tuesday that its Consumer Confidence Index rose 15 points to 56.0. That’s up from a revised 40.9 in October _ the lowest level since the recession _ and the biggest jump since the 59.2 reading in July. The November number is encouraging, but far below the reading of 90, which indicates an economy on solid footing.

The confidence numbers are widely watched by economists because consumer spending accounts for 70 percent of economic activity. The confidence of U.S. consumers slipped after the summer amid renewed fears about a second recession. But Americans, who have been grappling with high unemployment and a weak housing market, have shown that they are feeling much more comfortable spending. Over the past weekend, for instance, they spent more than they ever have before during Black Friday weekend, the traditional start of the holiday shopping season.

“Consumers appear to be entering the holiday season in better spirits, though overall readings remain historically weak,” said Lynn Franco, director of The Conference Board Consumer Research Center in a statement low fee cash advance.

Franco noted that consumers’ assessment of current conditions improved after six months of steady declines. Consumers’ anxiety regarding the short-term outlook for business conditions, jobs and income prospects eased considerably.

One barometer of the index, which measures how shoppers feel now, rose to 38.3 from 27.1. The other gauge, which measures how shoppers say they will feel over the next six months, rose to 67.8 from 50.0.

Consumers have several reasons to be more confident as there have been some signs of improvement in the economy. Earlier this month, for instance, the Labor Department reported that the job market improved modestly as unemployment rate nudged down to 9 percent in October from 9.1 percent in September. The month marked the 13th consecutive month of job gains.

Source

November 13, 2011

Berlusconi ally won’t back a Monti govt in Italy

Filed under: Loans, stocks — Tags: , , , — Silver @ 7:44 am

Umberto Bossi, the longtime ally of former Italian premier Silvio Berlusconi, says his Northern League party won’t back any government led by economist Mario Monti “for now.”

Bossi says he told Italy’s president that his party will be a “vigilant” opposition to any Monti government until the economist spells out his program to rescue Italy’s troubled economy.

Berlusconi resigned Saturday after Italy came under enormous pressure for its sovereign debt.

Bossi says “for now, we said no online pay day loans.” He adds when Monti reveals his policies, the League will decide on a measure-by-measure basis.

Italy’s president could ask Monti to try to form a government to rescue Italy from looming financial disaster after talks with all parties Sunday.

Source

November 5, 2011

FDA clears blood thinner for irregular heart beat

Filed under: lenders, stocks — Tags: , , , — Silver @ 12:52 am

More than 2 million new U.S. patients will be eligible to receive a next-generation blood thinner drug called Xarelto, after the Food and Drug Administration approved the medication to treat a common heart problem that can lead to stroke.

Federal health officials approved the drug from Johnson & Johnson and Roche to prevent strokes in patients with atrial fibrillation, a condition that causes the heart’s upper chambers beat chaotically and ineffectively. The irregular heartbeats can cause blood clots which travel to the brain, blocking blood flow and occasionally causing a stroke.

“This approval gives doctors and patients another treatment option for a condition that must be managed carefully,” said Dr. Norman Stockbridge, director of FDA’s cardiovascular and renal products division.

The once-a-day pill was first approved in July to prevent strokes in patients receiving hip and knee replacements. Today’s approval expands the drug’s indication to the much larger group of roughly 2.2 million Americans with atrial fibrillation.

For more than half a century, atrial fibrillation patients have relied on the tough-to-use blood thinner warfarin, sold under the brand name Coumadin. Doctors often have trouble gauging the right dose of the drug for each patient. Too much warfarin can cause dangerous internal bleeding, and too little can result in strokes.

In a setback for the drugs’ developers, the FDA did not approve a manufacturer-requested claim that Xarelto was superior at preventing stroke and blood clots when compared with warfarin. Instead the FDA states that the companies’ 14,000-patient study showed Xarelto and warfarin were about the same in preventing stroke creditreport.

Also, the FDA added a boxed safety warning, the most serious kind, stating that patients should not stop taking Xarelto without notifying their doctors first. Discontinuing the drug can increase the risk of stroke.

Numerous drugmakers have been working to develop an updated alternative to warfarin, one of the most widely-used medications in the U.S. Last year U.S. pharmacies filled 32 million prescriptions for warfarin, according to data tracker IMS Health.

Last October, the FDA approved the first alternative to warfarin for atrial fibrillation _ Pradaxa, known chemically as dabigatran, made by the German company Boehringer Ingelheim. That drug’s label states that the daily pill “significantly reduced” stroke and blood clots in a study of 18,000 patients.

In September a panel of outside advisers to the FDA voted 9-2 to recommend approval for use in atrial fibrillation. The panel’s recommendation came despite questions from FDA scientists about the reliability of some data submitted on Xarelto.

Xarelto is the first in a new class of blood thinning drugs that work by blocking a clotting protein called factor Xa. Older blood thinners, including warfarin, work by preventing blood platelets from sticking together.

Known chemically as rivaroxaban, Xa was discovered by German drugmaker Bayer and co-developed with New Brunswick, N.J.-based J&J. J&J holds U.S. marketing rights to the drug while Bayer markets the drug in the rest of the world.

October 31, 2011

Qantas returns to the skies after fleet grounding

Filed under: news, stocks — Tags: , , , — Silver @ 4:52 am

Qantas Airways planes returned to the skies Monday after an Australian court ruled on a bitter labor dispute that had prompted the world’s 10th-largest airline to ground its entire fleet.

A flight from Sydney to Jakarta, Indonesia, took off shortly after Australia’s Civil Aviation Safety Authority gave the “Flying Kangaroo,” as the Australian flag carrier is known, the all-clear to resume flying.

Qantas said in a statement it still expected some delays as it worked to clear the backlog of customers affected by the nearly 48-hour grounding. The airline is adding extra flights and expects its schedule to return to normal within one or two days.

The grounding disrupted the travel plans of tens of thousands of people across the world, and Qantas passengers were gathering at airports in Australia, Los Angeles and elsewhere in the hopes of finally getting to their destinations.

The airline’s resumption of flights comes around 12 hours after an emergency ruling by an arbitration court ended weeks of strikes and canceled a staff lockout.

The court ruling was a major victory in the airline’s battle with unions representing pilots, aircraft mechanics, baggage handlers and caterers, whose rolling strikes have forced the cancellation of 600 flights in recent months, disrupted travel for 70,000 passengers and cost Qantas 70 million Australian dollars ($75 million).

But some aviation experts said the surprise grounding of all 108 planes on Saturday, at a cost of $20 million a day, has hurt the Australian flagship carrier’s reputation around the world. Moody’s Investors Service said it could downgrade the airline’s credit ratings as the weekend’s events could hurt bookings, profits and the value of the Qantas brand.

Still, the stock market welcomed the weekend developments as allowing the airline to focus on its long-term strategy. Qantas shares on Monday jumped 4.3 percent to AU$1.61 on the stock exchange in Sydney.

Henry Harteveldt, an airline industry analyst in San Francisco, predicts the shutdown will do long-term damage to the Qantas name by hurting its reputation for reliability.

“A lot of travelers won’t take a chance and will book away to Virgin Australia, Air New Zealand and other airlines,” Harteveldt said. “Brand loyalty in the airline business is very low, and there is so much competition.”

Before the court ruling, Virgin Australia said it was scheduling extra flights and offering 20 percent fare discounts to help stranded Qantas passengers through Thursday.

If Qantas loses customers, that could also hurt partners in its alliance of global airlines, including American Airlines. A rival alliance that includes Air New Zealand and is led by United Continental Holdings Inc. could benefit, as could a third group of airlines that includes several major Asian carriers and is led by Delta Air Lines Inc. and Air France-KLM.

CEO Alan Joyce praised the court ruling, which prevents unions from taking any further strike action over their demands for pay hikes and job security clauses under news contracts being negotiated. The strikes have been blamed for a sharp decline in the airline’s future bookings.

“The important thing is that all industrial action is now over and we have certainty,” Joyce told reporters in Sydney.

“We will be returning to business as usual over the next 24 hours,” he said.

Other industry veterans said the lockout was a daring move that will pay off for Qantas, which wants to expand the low-cost, low-fare model that it uses at its Jetstar Airways subsidiary business cards design.

Jetstar has extensive routes to Southeast Asia and Japan, and lower costs than Qantas. But Qantas unions fear that expansion of low-cost airlines will result in Australian jobs being sent overseas. Joyce hopes to bend the unions closer to the company’s vision for growth by tapping into Asian markets.

“It was a very shrewd move by their CEO to force the issue and stop the potential deterioration of the brand,” said Mo Garfinkle, an airline consultant who has worked for Qantas rival Virgin Australia. “In the end, it will benefit Qantas financially.”

Garfinkle said the short duration of the fleet grounding will help Qantas get back up to full speed quickly, cutting its losses.

Prime Minister Julia Gillard on Monday described the grounding as “extreme,” while Transport Minister Tony Albanese has sharply criticized Joyce for giving the government only three hours notice of his plans.

The Australian government, angered by a lack of warning of the grounding, had called an emergency court hearing on Saturday night to end the work bans for the sake of the national economy.

The three judges heard more than 14 hours of testimony from the airline, the government and unions. Workers have held rolling strikes and refused overtime work for weeks out of worry that some of Qantas’ 32,500 jobs would be moved overseas in a restructuring plan.

The unions wanted the court to temporarily suspend the employee lockout so that strike action could resume if negotiations in the labor dispute failed to progress. But the airline said the strikes had devastated the airline’s reputation for reliability and that the threat needed to be removed permanently before customers would return.

Tribunal President Geoffrey Giudice said the panel decided that a temporary suspension would still risk Qantas’ grounding its fleet in the future and would not protect the tourism and aviation industries from damage.

Qantas is the largest of Australia’s four national domestic airlines, and the grounding affected 108 planes in 22 countries.

About 70,000 passengers fly Qantas daily, and would-be fliers this weekend were stuck at home, hotels or airports, or even had to suddenly deplane when Qantas suspended operations. More than 60 flights were in the air at the time but continued to their destinations, and Qantas was paying for passengers to book other flights.

Qantas infuriated unions in August when it said it would improve its loss-making overseas business by creating an Asia-based airline with its own name and brand. The five-year restructure plan will cost 1,000 jobs.

The airline also said in August that it had more than doubled annual profit to AU$250 million but warned that the business environment was too challenging to forecast earnings for the current fiscal year.

Qantas is the 10th-largest airline in the world by passenger miles flown, according to the International Air Transport Association, an airline trade group.

_____

Associated Press writers David Koenig from Dallas, Texas, and Andrew Dalton from Los Angeles contributed to this report.

Source

August 4, 2011

GM to invest $117M in Oshawa to build Cadillac XTS

Filed under: Finance, stocks — Tags: , , , — Silver @ 12:16 pm

OSHAWA

July 27, 2011

Fed survey: Growth slows across much of the US

Filed under: money, stocks — Tags: , , , — Silver @ 1:44 pm

The economy worsened in about half the country earlier this summer because of weak home sales and signs of a slowdown in manufacturing.

A Federal Reserve survey said Wednesday that seven of the Fed’s 12 bank regions reported slower growth in June and early July compared with the spring. That’s a worse showing than in the previous survey.

Of the remaining five districts, four reported modest growth. A fifth, the Minneapolis district, said its economy was disrupted by bad weather and the shutdown of Minnesota’s state government.

The job market remained weak in most districts, the report said. Employers added few jobs in June, the government said earlier this month.

Droughts and severe flooding badly hampered seven districts with large agricultural sectors, the report said.

Manufacturing output rose overall. But many districts reported only “steady or slowing” growth, the Fed’s report said. Only two districts reported rising manufacturing activity. Companies in three districts _ Philadelphia, Richmond and Atlanta _ reported slower growth.

The overall weak picture of the national economy echoes recent data on hiring and manufacturing. Economists expect growth for the April-June quarter, which will be reported Friday, to fall below 2 percent, the second straight quarter of anemic expansion.

The report, known as the “Beige Book,” is based on anecdotal information gathered by officials at the 12 Fed regional banks. It is released eight times a year and provides an on-the-ground snapshot of the economy. Wednesday’s report covered the roughly seven weeks between May 27 and July 15.

Source

July 24, 2011

Top local public companies: Revenue

Filed under: marketing, stocks — Tags: , , , — Silver @ 3:40 am

Rank Company Revenue

1 Express Scripts* $45 billion

2 Emerson* $21 billion

3 Monsanto* $10.5 billion

4 Reinsurance Group of America* $8.3 billion

5 Ameren* $7.6 billion

6 Charter Communications* $7.1 billion

7 Peabody Energy* $6.9 billion

8 Centene* $4 pay day loan lenders.4 billion

9 Energizer Holdings $4.2 billion

10 Ralcorp Holdings $4.0 billion

* Fortune 500 member

Based on fiscal year 2010 data

Source

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